Confidence is that feeling by which the mind embarks in great and honorable courses with a sure hope and trust in itself.
Cicero
Currently, there are 5.8 million individuals in the U.S. living with Alzheimer’s. This disease and other forms of dementia take the lives of one in three seniors – more than prostate and breast cancer combined. Alarmingly, the statistics are only worsening: within 30 years, the number of people living with Alzheimer’s is anticipated to jump to nearly 14 million. [1]
Although all forms of cancer, heart disease, and stroke may take more lives than Alzheimer’s currently, few people – if anyone – can say they know an Alzheimer’s survivor. While survivor rates are improving for these other conditions, Alzheimer’s deaths are only increasing. For example, between 2000 and 2017, deaths from heart disease have decreased by 9%. In that same period, Alzheimer’s-related deaths have increased 145%. [2]
As the world waits for a cure, leaders in wellness optimization – including the clinical team from Cenegenics – are urging individuals to start considering their own risk factors and making healthy choices to safeguard their cognitive wellness now. Unfortunately, there have been no drugs that have proven to be effective for treating Alzheimer’s, and a genuinely new drug for the disease has not been approved in over 15 years. [3] Clearly, we cannot take a single-pill approach to addressing this epidemic. What we need instead is a comprehensive approach to address the root causes of this disease. Below, discover the underlying factors that can help shape Alzheimer’s prevention initiatives over the coming years.
Alzheimer’s disease is a type of dementia that affects memory, thinking, and behavior. Symptoms typically develop slowly and over time, and eventually affect existing memories and a person’s ability to make new memories, personality traits, and the ability to complete daily activities.
This form of dementia is a result of two factors: the development of plaques made from amyloid-beta proteins between nerve cells, as well as tangles, or tau, inside the cells. The accumulation of amyloid-beta cells creates sticky plaques, which destroy synapses.
One of the main risk factors for Alzheimer’s is the ApoE4 gene variant. Having this variant from one parent can increase risk by 30%, while two copies can increase the lifetime risk to 50% to 90%. Non-carriers also have a lifetime risk of 9%, however. [4]
Alzheimer’s is broken down into three main types:
It’s important to note that many cases may present as a combination of Types 1 and 2, with chronically elevated glucose leading to increased inflammation, as well as high insulin secretion.
As we saw in the previous section, one form of Alzheimer’s is more inflammatory, while one is more atrophic, and the final appears to be environmental. With this in mind, it becomes apparent that a range of factors influences the disease, including:
There are a number of ways these biomarkers can be picked up through diagnostic testing. For example, brain scans, a complete blood count (CBC), metabolic and thyroid panels, B12 levels, and changes in daily abilities may all be monitored to look for indicators that could point towards an elevated risk for Alzheimer’s.
Because the factors that contribute to Alzheimer’s span far and wide, the best approach to take is the most comprehensive. In-depth diagnostics will therefore give the most illuminating picture of risk, which can also help to reveal the biomarkers which are at suboptimal levels but can be managed. This then helps clinicians create a detailed action plan to help patients take control of their risks.
For example, clinicians can test for the following factors which play a role in Alzheimer’s development:
Although factors such as ApoE status can’t be controlled, many other biomarkers can be managed. For instance, homocysteine levels can be controlled through the use of individually-dosed nutraceuticals, including vitamins B12, B6, and folate. Elevated glucose and insulin, which are two of the most important factors that can influence disease-causing inflammation, can also be addressed through specific dietary and lifestyle changes. In the final section, we’ll explore some of the specific tactics that can be used to formulate a personalized Alzheimer’s prevention roadmap.
There are many different ways people can take control of their Alzheimer’s risk. Here are the top 5 most powerful tactics:
While each individual’s action plan for minimizing Alzheimer’s risk will look different, below are 7 prevention strategies you can start to implement effectively:
Alzheimer’s disease is on the rise, and while there may currently be no cure or effective treatment, there are still risk factors within our control to change. Aside from genetic influences, factors such as inflammation, the environment, and lifestyle choices can all be optimized to minimize Alzheimer’s risk. Yet, we can’t develop an individualized action plan without first knowing where our health stands currently.
For this reason, undergoing a comprehensive Elite Health Evaluation is the first step in understanding and controlling your risk for Alzheimer’s and other serious diseases. And, as the important precursor to all Cenegenics programs, our Elite Health Evaluation provides the key indicators our clinical team needs to cultivate a comprehensive, individualized plan for each of our patients. If you’re interested in having your evaluation completed, contact your nearest Cenegenics location today.
Our world-class physicians create a personalized plan to help you feel 10+ years younger. You’ll be more energetic, lose weight, sleep better, have more libido, and think more clearly. Click below to schedule a free consultation with one of our physicians. It’s quick + easy.
Key Resources
This guide was produced with contributions from the following key resources:
The Cenegenics Education and Research Foundation
The Textbook of Age Management Medicine Volume 1: Mastering Healthy Aging Nutrition, Exercise, and Hormone Replacement Therapy
The Cenegenics Education and Research Foundation
The Textbook of Age Management Medicine Volume 2: Mastering Healthy Aging Nutrition, Exercise, and Hormone Replacement Therapy
Textbook Authors:
Jeffrey Park Leake, M.D., CPT
Dr. Jeffrey Park Leake is a Partner and Director of Education at Cenegenics Elite Health specializing in age management and wellness. Having trained hundreds of physicians worldwide, Dr. Leake is also the Director of Education for the Clinical Strategies for Healthy Aging course at AMM Educational Foundation.
Todd David Greenberg, M.D., CSCS
Dr. Todd Greenberg is a practicing physician with a broad range of expertise, including wellness, exercise, sports injuries, and MRI of sports injuries. He is a Radiology Clinical Associate Professor at the University of Washington.
Additional Resources
Mental Acuity: How to Improve Mental Sharpness with Cenegenics
Are You Aware of the Impact Stress Has?
Key to Health & Wellness: What is Cenegenics?
Understanding Preventive Care: Age Management vs Anti-Aging
What is Age Management Medicine?
Youth is a Feeling – Not a Number
Understanding How to Deal with Stressors
This is How Your Body is Reacting to Stress
Long Term Effects of Anxiety on the Body
Causes and Symptoms of Anxiety Disorders
Learn About Vitamin K – Including Beneficial Foods with Vitamin K
7 Tips To Make Any Meal Healthier
What is Metabolic Syndrome? Symptoms, Diagnosis, & Treatment
The Role of Vitamins and Minerals as Micronutrients
Recognizing Your Risk Factors of Type 2 Diabetes
References
[1] Alzheimer’s Disease Facts and Figures. Alzheimer’s Association®. 2019. Retrieved from URL: https://www.alz.org/alzheimers-dementia/facts-figures
[2] Alzheimer’s Disease Facts and Figures; see above.
[3] Alzheimer’s Association®.
[4] “Alzheimer’s Prevention” What You Can Do to Reduce Your Risk.” Cenegenics. 30 Sept. 2019. Retrieved from URL: https://www.youtube.com/watch?v=9ijGhqdYMzI
[5] “Alzheimer’s Prevention” What You Can Do to Reduce Your Risk.” Cenegenics. 30 Sept. 2019. Retrieved from URL: https://www.youtube.com/watch?v=9ijGhqdYMzI
Rudy Inaba is Cenegenics’ Vice President of Health Performance. He is a recognized fitness and sports nutrition consultant with nearly 15 years of experience in clinical exercise physiology and lifestyle management. After pursuing his Master of Science in Clinical Exercise Physiology at the University of Nevada Las Vegas, Rudy joined Cenegenics where he leads 19 clinical locations nationwide in their advancements in kinesiology, nutritional biochemistry, and their analyses of industry research & market trending.