Peptides are one of the most talked-about topics in longevity and performance medicine right now and one of the most misrepresented. Cenegenics built this series to cut through the noise: 33 compounds, explained clinically, with expert commentary on each one.

The peptide space is loud and most of it isn’t clinical

Search for almost any peptide today and you’ll find a mix of Reddit threads, supplement marketing copy, anecdotal fitness forums, and occasionally a legitimate study buried somewhere in the middle. The signal-to-noise ratio is poor. Claims are inflated. Mechanisms are oversimplified. Side effects are glossed over.

That’s a problem, because peptides are genuinely interesting compounds. The clinical research behind many of them is real, peer-reviewed, and worth understanding. But the way that research gets filtered through online media usually strips out the nuance that makes it useful.

Cenegenics operates differently. We have 29 years of physician-led practice, 50,000+ members, and a clinical team that evaluates compounds based on evidence  not trends. This series is an extension of that standard.

What you’ll find in each post

Every post in this series covers one compound and follows the same structure, so you always know where to find what you’re looking for:

• What it is: A direct, plain-English answer to the most basic question — written to be clear whether you’re a patient, a physician, or somewhere in between.
• How it works: The mechanism of action, explained without unnecessary jargon but without skipping the science either.
• Clinically observed benefits: What the research actually shows — nothing added, nothing inflated. Every benefit listed traces directly to published clinical literature.
• Administration formats: How each compound is compounded and delivered, from injections to nasal sprays to troches.
• Frequently asked questions: The questions patients and practitioners actually ask, answered directly.
• Clinical research: A summary of the peer-reviewed foundation behind the compound.

You will not find speculative benefits, exaggerated claims, or mechanisms extrapolated beyond what the literature supports. If it isn’t in the clinical record, it isn’t in these posts.

Rudy’s commentary, why it’s here and why it matters

At the end of every post in this series, you’ll find a section called Rudy Commentary.

Rudy Inaba is the Senior Vice President of Performance Health at Cenegenics. His role sits at the intersection of clinical protocol, patient outcomes, and the practical application of longevity medicine at scale. He has reviewed and advised on peptide protocols across thousands of patient cases.

His commentary is not a summary of the research above it. It’s a expert’s perspective, the kind of context that only comes from working with real patients over time. What does this compound actually look like in a clinical setting? Where does the research align with patient experience? Where are the gaps? What should someone actually know before asking their physician about this?

That layer of applied clinical insight is what separates this series from anything else currently published on these compounds.

How the series is organized

33 compounds are a lot to navigate. We’ve grouped them into eight categories so you can go directly to what’s most relevant to your health priorities:

• Fat Loss & Metabolic — compounds targeting body composition, insulin sensitivity, and metabolic function
• Growth Hormone & Body Composition — GHRH analogs and GH secretagogues that influence lean mass, recovery, and IGF-1
• Cognitive & Neurological — nootropics, neuroprotective agents, and compounds targeting mood, memory, and focus
• Anti-Aging & Longevity — compounds with research in cellular repair, telomere biology, and lifespan extension
• Gut Health & Anti-Inflammatory — peptides targeting intestinal integrity, mucosal healing, and systemic inflammation
• Sexual Health — compounds addressing libido and sexual function in men and women
• Immune Support — thymic peptides and immune modulators
• Hair Health — topical compounds with research in follicle stimulation and androgenic alopecia

Who this series is for

If you’re a patient exploring peptide therapy for the first time, this series will give you a reliable foundation, one you can bring into a conversation with your physician rather than walking in with something you read on a forum.

If you’re already working with a practitioner and considering specific compounds, the clinical research sections and FAQ entries are designed to answer the questions that come up most in those conversations.

If you’re a clinician or health professional, the mechanism and research sections are written at a level that respects your background, and Rudy’s commentary is written specifically for the practitioner perspective.

In every case, the goal is the same: give you accurate, clinically grounded information on compounds that are generating real interest — and deserve a serious treatment.

The series begins now. Explore by category, or start with whichever compound brought you here.

 

[Related: See our full Peptide Therapy Series]

 

These statements have not been evaluated by the Food and Drug Administration. The compounds discussed in this series are not intended to diagnose, treat, cure, or prevent any disease. This content is for informational purposes only and does not constitute medical advice. Peptide therapy should only be pursued under the supervision of a licensed physician.