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How to Slow Down & Even Decrease Biological Age

Discover 5 Practical Tips to Support Your Body’s Natural Aging Process

September 9, 2025 - 7 Min Read

Rudy Inaba

Rudy Inaba

Senior Vice President of Performance Health

Man and woman talking about biological age

While chronological age counts the number of years you’ve been alive, biological age tells a more comprehensive story about your health. It assesses specific physiological measures to establish an individual’s wellness relative to their chronological age. For example, a healthy individual in their 40s may have a lower biological age than someone of poorer health in their 30s, despite having a higher chronological age. In other words, biological age tells us how well our bodies are functioning – and how likely we are to develop age-related conditions – based on key biomarkers.

Researchers have looked at many factors when attempting to come up with a widely accepted measurement for biological age. Some believe that it should be measured based on molecular markers of inflammation, including C-reactive protein. [1] Others feel biological age encompasses mortality, the ability to function, and the need for therapies and interventions to extend health (or lack thereof). [2] Others still feel that biological age is marked by bodily changes which take place, including persistent, low-grade inflammation despite a lack of any known pathogens, dysfunction at the cellular level, stem cells’ impeded ability to repair tissue, and cells’ decreasing ability to proliferate. [3]

Science-Based Biological Age Management

Most recently, Yale School of Medicine researcher, Morgan Levine, Ph.D., and her team have come up with nine biomarkers that appear to have the greatest impact on lifespan, including:

  • Blood sugar levels
  • Immune and inflammatory measures
  • Kidney and liver measures

When plugged into an advanced algorithm, these metrics yield a biological age reading which acts as a “highly robust predictor of both morbidity and mortality outcomes.” It does more than just tell you the rate at which you’re aging, however; it can also determine the therapies and lifestyle interventions that can be introduced now to lower your risk for serious diseases such as cardiovascular disease and coronary heart disease. As a result, understanding your biological age can pave the way for not only a longer lifespan but also an extension of the health span, which translates to an improved quality of life at every age. [4] Understanding what lifestyle changes can lower your risk of serious diseases can help reverse your biological age.

As leaders in age management, Cenegenics has closely looked at biological aging for the past 23 years. One of our physicians has authored the textbook used to teach physicians Age Management; in fact, we pioneered the concept as a medical specialty. We therefore firmly support Yale Medical School’s standpoint that there’s plenty you can do to take control of your biological age. Here are just a few ways we can help you decrease your biological age.

Maintain a Healthy Weight

Many experts agree that chronic inflammation is a characteristic of higher biological age. In people who are obese, fat tissue acts as an active endocrine organ, contributing to the production of TNF-alpha proteins, a biomarker of low-grade, systemic inflammation. This inflammation appears to explain the link between obesity and many co-morbidities, including:

  • Cardiovascular disease
  • Stroke
  • Heart attack
  • Diabetes
  • Certain types of cancer. [5]

Fortunately, Cenegenics helps patients lose weight if needed and maintain a healthy weight over the long term. We analyze specific biomarkers and perform in-depth body composition analyses, understanding that health is about more than just one number. We then provide tailored recommendations to help our patients control their weight. With this highly scientific approach to work toward getting your body perfectly tuned at the cellular level, we prompt ideal function and thus decrease and reverse biological age.

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Improve Sleep Quality

Sleep deprivation, too, is linked to inflammation which could increase biological age. In studies, individuals whose sleep was restricted by 25 to 50% of a normal eight-hour cycle experienced inflammatory cytokines, which are directly linked to an elevated risk for metabolic syndrome. [6] The prevalence of metabolic syndrome increases with chronological age, but it’s also linked to increased biological age as well. It bears a strong link with an increased risk of diabetes, cardiovascular disease, and all-cause mortality. [7]

Promoting quality sleep is one of the pillars of the Cenegenics program. We believe that sleep is important at every age, and supports not only optimal physical health but also strong brain function and emotional wellness. Increasing the amount of sleep can help decrease biological age.

Sleep deprivation can affect the body’s insulin response, increase the risk of obesity, and impede immune system functionality. [8] This is critical, considering the fact that some experts believe immune system changes have a direct role in the pace of biological aging. [9] Fortunately, the Cenegenics team helps patients develop targeted sleep management strategies to improve both the duration and quality of their slumber.

Tailor to Unique Biomarkers

To some degree, genetics are also believed to play a role in the rate of biological aging. After all, some people are naturally predisposed to certain conditions based on hereditary factors. While we can’t change our genetic profile, we can arm ourselves with as much knowledge as possible about genetic factors and make strategic choices to support the best possible outcomes with these factors in mind.

For instance, Cenegenics offers genetic testing options that can assess for everything from Alzheimer’s risk to food sensitivities. Our clinicians can then prescribe lifestyle modifications that can help to control your risk of developing serious conditions and give you the power to take a comprehensive, preventive approach against disease.

Maintaining Healthy Hormone Levels

Hormone health is also related to biological age. At Cenegenics, we employ strategies to help patients achieve optimal hormone levels, reversing the biological age by rebalancing the body to where it was in their 20s and 30s. While the aging process is complex and still being studied, we know that many of the changes that take place in the body are influenced by declining hormone levels.

Fortunately, minimizing the risk of disease, frailty, and disability is possible through healthy lifestyle practices that promote hormone optimization, including:

  • Stress management
  • Regular physical activity
  • Nutritious dietary choices
  • Effective sleep practices

When clinically indicated, our physicians can also recommend hormone replacement therapy options to pursue hormone balance and improved overall health in specific populations.

Let Cenegenics Reverse Your Biological Age – In Conclusion

It isn’t a coincidence that these very factors are the pillars of the Cenegenics program. Not only do our experts take a research-based approach to help our patients reach and maintain a healthy weight, improve their sleep quality, and optimize their health in many other important ways, but we also look at each individual’s biomarkers for a better understanding of their biological age. In doing so, we tailor recommendations to your precise needs, allowing you to feel your best both now and at every age.

Although it’s impossible to turn back the chronological clock, Cenegenics can give you the tools to take control of your biological age, and thus the future. By promoting improved health across a number of key areas, including sleep, diet, and lifestyle habits, our clinicians help patients make wiser, future-focused health decisions that help them feel better both now and years down the road.

All of this is included in the Cenegenics cost of program membership, along with the many other benefits that come with being one of our patients. But don’t take our word for it – see what other satisfied patients have to say on our Cenegenics reviews page. As you’ll see, most patients begin to feel dramatically better within 30 to 60 days on the program. We’re also the doctors who other doctors trust, with physicians and their families making up 25% of our patient population. Once you’re ready to start taking control of your biological age, contact your nearest location for more information.

Rudy Inaba

Contributor: Rudy Inaba, Senior Vice President of Performance Health

Rudy Inaba is Cenegenics’ Senior Vice President of Performance Health. He is a recognized fitness and sports nutrition consultant with nearly 15 years of experience in clinical exercise physiology and lifestyle management. After pursuing his Master of Science in Clinical Exercise Physiology at the University of Nevada Las Vegas, Rudy joined Cenegenics where he leads 19 clinical locations nationwide in their advancements in kinesiology, nutritional biochemistry, and their analyses of industry research & market trending.

"Life is about growing old and feeling young."

Anushka Singh

Reference Links:

"Overview of the Immune System. National Institute of Allergy and Infectious Diseases."
https://www.niaid.nih.gov/research/immune-system-overview
"The Many Causes Of Immune Deficiency. German Society for Immunology."
https://www.sciencedaily.com/releases/2009/09/090914111540.htm
"Immune System Disorders. University of Rochester Medical Center Rochester, NY."
https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentID=123&ContentTypeID=134
"What Is Inflammation? Szalay, Jessie. LiveScience."
https://www.livescience.com/52344-inflammation.html
"How to boost your immune system. Harvard Medical School."
https://www.health.harvard.edu/staying-healthy/how-to-boost-your-immune-system
"Sedentary Behavior and Adiposity-Associated Inflammation The Multi-Ethnic Study of Atherosclerosis. A. Allison, Matthew MD, MPH, Jensky, Nicole E. PhD, Marshall, Simon J., PhD, Bertoni, Alain G. , MD, MPH, and Cushman, Mary MD. National Institute of Medicine."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244676/
"9 Surprising Ways You’re Weakening Your Immune System. Dallas, Mary Elizabeth and Marcellin, Lindsey MD, MPH. Everyday Health."
https://www.everydayhealth.com/news/9-surprising-ways-youre-weakening-your-immune-system/
"Sleep deprivation effect on the immune system mirrors physical stress. National Sleep Foundation."
https://www.sleepfoundation.org/articles/sleep-deprivation-effect-immune-system-mirrors-physical-stress
"The immune system and overtraining in athletes: clinical implications. AC Hackney and Koltun KJ. National Institute of Health."
https://www.ncbi.nlm.nih.gov/pubmed/23540172
"Evaluation of immune response after moderate and overtraining exercise in wistar rat. Zahra Gholamnezhad, Abolfazl Khajavi Rad, Mohammad Hossein Boskabady, Mahmoud Hosseini, and Mojtaba Sankian. National Institutes of Health"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938879/

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Cenegenics Member Refund, Return, Cancellation and Payment Policy

Effective Date: August 19, 2026

1. Purpose and Scope
This Policy governs refunds, returns, cancellations, membership freezes, recurring payments, products, services, diagnostics, prescriptions, and related matters associated with Cenegenics programs and memberships.

2. Definitions
“Member” means any individual enrolled in a Cenegenics program. “Program Fees” include membership fees, enrollment fees, recurring subscription fees, assessment fees, coaching fees, and other fees charged by Cenegenics. “Services” include physician consultations, coaching, diagnostics, care coordination, telehealth services, and related offerings.

3. Membership Fees and Refunds
Program Fees are non-refundable once charged except as expressly required by law or approved by Cenegenics. Voluntary cancellation does not entitle a member to a refund of previously paid fees; except to the extent required by applicable federal, state, or local law. Approved refunds will be processed within thirty (30) days of approval using the Member’s original payment method, unless otherwise required by applicable law.

4. Membership Freezes and Pauses
Cenegenics may approve membership freezes or pauses in limited circumstances. Approval, duration, eligibility, and any associated fees shall be determined solely by Cenegenics. Freezes do not create any entitlement to refunds or credits.

5. Appointment Cancellations and Rescheduling
Performance Health Assessments and other designated appointments require at least fourteen (14) calendar days’ notice for cancellation or rescheduling. Late cancellations or rescheduling may incur a fee of up to $500, representing a reasonable estimate of Cenegenics’ actual costs and losses resulting from the late cancellation or rescheduling, including, without limitation, reserved provider time, facility costs, and administrative expenses. Appointment deposits are non-refundable and expire after twelve (12) months of payment.

6. Non-Prescription Products
All sales of supplements, wellness products, merchandise, and other non-prescription products are final and non-refundable unless otherwise required by law.  Members may request a replacement or refund for products that are defective, damaged during shipment, or materially different from the product ordered, provided the Member notifies Cenegenics within fourteen (14) days after delivery.

7. Prescription Products
Prescription medications, compounded medications, hormone therapies, peptides, and other prescription products are non-returnable once dispensed or shipped consistent with applicable federal and state pharmacy laws. Refunds may be granted only in limited circumstances such as recalls, fulfillment errors, prescribing errors, or pharmacy errors.

8. Prescription Eligibility and Dispensing Disclaimer
Membership, physician consultations, testing, or program participation do not guarantee receipt of any prescription medication, hormone therapy, peptide, compounded medication, treatment, or clinical intervention. Prescribing decisions are made solely by licensed providers based on clinical judgment, medical necessity, applicable laws, and patient-specific factors. Prescription fulfillment is further subject to pharmacy acceptance, inventory availability, state and federal law, and shipping restrictions.

9. Telehealth Services
Telehealth services may not be available in all states or jurisdictions. Availability of telehealth services is subject to provider licensure requirements, applicable laws, technology limitations, and clinical appropriateness. Fees paid for telehealth evaluations are generally non-refundable once services have been rendered.

10. Laboratory Testing and Diagnostics
Laboratory testing, specialty testing, imaging, and diagnostic services are non-refundable once processing, specimen collection, scheduling, or fulfillment has commenced. Cenegenics may provide replacement testing in cases of testing errors or defective materials.

11. Services Already Rendered
No refunds shall be issued for physician consultations, coaching services, prescription reviews, diagnostic interpretation, care coordination, telehealth visits, or any other professional services already rendered.

12. Unused Services and Membership Benefits
Unused visits, coaching sessions, assessments, promotional credits, loyalty benefits, and other membership benefits have no cash value, are non-transferable, and may expire upon cancellation, termination, or lapse of membership.  To the extent an account balance constitutes funds that are subject to applicable state unclaimed property laws, such funds shall be handled in accordance with applicable state unclaimed property laws.

13. Automatic Renewal and Recurring Payments
By enrolling in a recurring membership or subscription, the Member authorizes Cenegenics to charge the payment method on file for recurring fees until properly canceled pursuant to the Membership Agreement. Members are responsible for maintaining accurate payment information.

14. Failed Payments
Members are responsible for maintaining valid payment information.  Cenegenics reserves the right to assess reasonable fees for returned payments, insufficient funds, or failed transactions, to the extent permitted by law.

15. Chargebacks and Payment Disputes
Members are encouraged to contact Cenegenics before initiating any chargeback or payment dispute so that Cenegenics may attempt to resolve the matter directly. Nothing in this Policy shall limit a Member’s rights under applicable law to dispute charges through the Member’s financial institution. 

16. Membership Termination by Cenegenics
Cenegenics reserves the right to suspend or terminate any membership or service relationship at any time for violations of applicable agreements, abusive conduct, non-payment, safety concerns, fraud, misuse of services, regulatory requirements, or other legitimate business reasons.

17. Discretionary Exceptions
Cenegenics may grant exceptions to this Policy in its sole discretion. Any exception granted in one instance shall not establish a precedent for future requests.

18. Travel, Illness, and Force Majeure
Travel disruptions, illness, family emergencies, weather events, acts of God, governmental actions, technology failures, supply chain disruptions, and similar events do not automatically entitle Members to refunds or fee waivers.

19. Governing Law and Venue
This Policy shall be governed by the laws of the state specified in the applicable Membership Agreement and shall be subject to the dispute resolution and arbitration provisions of the Membership Agreement.

20. Compliance with Applicable Law
Nothing in this Policy shall limit any rights that cannot be waived under applicable federal, state, or local law. To the extent any provision conflicts with applicable law, such provision shall be interpreted to comply with applicable law while preserving its original intent to the greatest extent possible.

21. Policy Modification
Cenegenics reserves the right to interpret, administer, amend, modify, or discontinue this Policy at any time, subject to applicable law. The most current version shall govern unless otherwise expressly stated in writing.